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Transcriptomic signatures of brain regional vulnerability to Parkinson’s disease

The molecular mechanisms underlying caudal-to-rostral progression of Lewy body pathology in Parkinson’s disease remain poorly understood. Here, we identified transcriptomic signatures across brain regions involved in Braak Lewy body stages in non-neurological adults from the Allen Human Brain Atlas....

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Detalles Bibliográficos
Autores principales: Keo, Arlin, Mahfouz, Ahmed, Ingrassia, Angela M. T., Meneboo, Jean-Pascal, Villenet, Celine, Mutez, Eugénie, Comptdaer, Thomas, Lelieveldt, Boudewijn P. F., Figeac, Martin, Chartier-Harlin, Marie-Christine, van de Berg, Wilma D. J., van Hilten, Jacobus J., Reinders, Marcel J. T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058608/
https://www.ncbi.nlm.nih.gov/pubmed/32139796
http://dx.doi.org/10.1038/s42003-020-0804-9