Dexmedetomidine Alleviated Endoplasmic Reticulum Stress via Inducing ER-phagy in the Spinal Cord of Neuropathic Pain Model

Studies demonstrated that spinal autophagy was impaired in spinal nerve ligation (SNL) rats. However, the relationship of endoplasmic reticulum (ER) stress and ER-phagy and whether dexmedetomidine (DEX) modulates ER-phagy remain unclear. In this study, male Sprague–Dawley (SD) rats and the SNL anima...

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Detalles Bibliográficos
Autores principales: Liu, Yongda, Wang, Shuang, Wang, Zhibin, Ding, Mengmeng, Li, Xingyue, Guo, Jiao, Han, Guang, Zhao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058658/
https://www.ncbi.nlm.nih.gov/pubmed/32184704
http://dx.doi.org/10.3389/fnins.2020.00090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058658/
https://www.ncbi.nlm.nih.gov/pubmed/32184704
http://dx.doi.org/10.3389/fnins.2020.00090

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