GPU-Accelerated Discovery of Pathogen-Derived Molecular Mimics of a T-Cell Insulin Epitope

The strong links between (Human Leukocyte Antigen) HLA, infection and autoimmunity combine to implicate T-cells as primary triggers of autoimmune disease (AD). T-cell crossreactivity between microbially-derived peptides and self-peptides has been shown to break tolerance and trigger AD in experiment...

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Detalles Bibliográficos
Autores principales: Whalley, Thomas, Dolton, Garry, Brown, Paul E., Wall, Aaron, Wooldridge, Linda, van den Berg, Hugo, Fuller, Anna, Hopkins, Jade R., Crowther, Michael D., Attaf, Meriem, Knight, Robin R., Cole, David K., Peakman, Mark, Sewell, Andrew K., Szomolay, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058665/
https://www.ncbi.nlm.nih.gov/pubmed/32184781
http://dx.doi.org/10.3389/fimmu.2020.00296

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058665/
https://www.ncbi.nlm.nih.gov/pubmed/32184781
http://dx.doi.org/10.3389/fimmu.2020.00296

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