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Targeting Circulating SINEs and LINEs with DNase I Provides Metastases Inhibition in Experimental Tumor Models

Tumor-associated cell-free DNAs (cfDNAs) are found to play some important roles at different stages of tumor progression; they are involved in the transformation of normal cells and contribute to tumor migration and invasion. DNase I is considered a promising cancer cure, due to its ability to degra...

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Detalles Bibliográficos
Autores principales: Alekseeva, Ludmila A., Sen’kova, Aleksandra V., Zenkova, Marina A., Mironova, Nadezhda L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058713/
https://www.ncbi.nlm.nih.gov/pubmed/32146418
http://dx.doi.org/10.1016/j.omtn.2020.01.035