Neddylation inactivation represses androgen receptor transcription and inhibits growth, survival and invasion of prostate cancer cells

Androgen receptor (AR) and its constitutively active variants (AR-Vs) have been extensively implicated in the progression and recurrence of prostate cancer, making them attractive targets in the treatment of this disease. Whether and how neddylation modification regulates AR, and the therapeutic imp...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaochen, Han, Sumin, Wilder-Romans, Kari, Sun, Grace Y., Zhu, Hong, Liu, Xiaoqiang, Tan, Mingjia, Wang, Gongxian, Feng, Felix Y., Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058827/
https://www.ncbi.nlm.nih.gov/pubmed/32145689
http://dx.doi.org/10.1016/j.neo.2020.02.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058827/
https://www.ncbi.nlm.nih.gov/pubmed/32145689
http://dx.doi.org/10.1016/j.neo.2020.02.002

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