Cargando…

Simplified drug efficacy screening system for sleep-disorder drugs using non-human primates

The most widely used animal models to develop sleep-disorder drugs are rodents, particularly rats and mice. However, unlike humans, these rodents are nocturnal. Thus, diurnal non-human primates represent a valuable and more translational animal model to study sleep. Although sleep-disorder drugs hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Sakai, Keita, Ishikawa, Akiyoshi, Mizuno, Yuri, Maki, Takehiro, Oda, Yasuhiro, Takahashi, Eiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058904/
https://www.ncbi.nlm.nih.gov/pubmed/32154428
http://dx.doi.org/10.1016/j.heliyon.2020.e03524