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Simplified drug efficacy screening system for sleep-disorder drugs using non-human primates
The most widely used animal models to develop sleep-disorder drugs are rodents, particularly rats and mice. However, unlike humans, these rodents are nocturnal. Thus, diurnal non-human primates represent a valuable and more translational animal model to study sleep. Although sleep-disorder drugs hav...
Autores principales: | Sakai, Keita, Ishikawa, Akiyoshi, Mizuno, Yuri, Maki, Takehiro, Oda, Yasuhiro, Takahashi, Eiki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058904/ https://www.ncbi.nlm.nih.gov/pubmed/32154428 http://dx.doi.org/10.1016/j.heliyon.2020.e03524 |
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