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Wnt5b integrates Fak1a to mediate gastrulation cell movements via Rac1 and Cdc42

Focal adhesion kinase (FAK) mediates vital cellular pathways during development. Despite its necessity, how FAK regulates and integrates with other signals during early embryogenesis remains poorly understood. We found that the loss of Fak1a impaired epiboly, convergent extension and hypoblast cell...

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Detalles Bibliográficos
Autores principales: Hung, I-Chen, Chen, Tsung-Ming, Lin, Jing-Ping, Tai, Yu-Ling, Shen, Tang-Long, Lee, Shyh-Jye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058935/
https://www.ncbi.nlm.nih.gov/pubmed/32097584
http://dx.doi.org/10.1098/rsob.190273