EXP2SL: A Machine Learning Framework for Cell-Line-Specific Synthetic Lethality Prediction

Synthetic lethality (SL), an important type of genetic interaction, can provide useful insight into the target identification process for the development of anticancer therapeutics. Although several well-established SL gene pairs have been verified to be conserved in humans, most SL interactions rem...

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Detalles Bibliográficos
Autores principales: Wan, Fangping, Li, Shuya, Tian, Tingzhong, Lei, Yipin, Zhao, Dan, Zeng, Jianyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058988/
https://www.ncbi.nlm.nih.gov/pubmed/32184722
http://dx.doi.org/10.3389/fphar.2020.00112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058988/
https://www.ncbi.nlm.nih.gov/pubmed/32184722
http://dx.doi.org/10.3389/fphar.2020.00112

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