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EXP2SL: A Machine Learning Framework for Cell-Line-Specific Synthetic Lethality Prediction
Synthetic lethality (SL), an important type of genetic interaction, can provide useful insight into the target identification process for the development of anticancer therapeutics. Although several well-established SL gene pairs have been verified to be conserved in humans, most SL interactions rem...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058988/ https://www.ncbi.nlm.nih.gov/pubmed/32184722 http://dx.doi.org/10.3389/fphar.2020.00112 |