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Protective Effects of the Soluble Epoxide Hydrolase Inhibitor 1-Trifluoromethoxyphenyl-3-(1-Propionylpiperidin-4-yl) Urea in a Rat Model of Permanent Middle Cerebral Artery Occlusion

Acute ischemic stroke is a serious disease that endangers human health. In our efforts to develop an effective therapy, we previously showed that the potent, highly selective inhibitor of soluble epoxide hydrolase called 1-trifuoromethoxyphenyl-3-(1-propionylpiperidin-4-yl) urea (TPPU) protects the...

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Detalles Bibliográficos
Autores principales: Zhang, Linlei, Xu, Shasha, Wu, Xiaoxiao, Muse, Farah Mohamed, Chen, Jiaou, Cao, Yungang, Yan, Jueyue, Cheng, Zicheng, Yi, Xingyang, Han, Zhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058996/
https://www.ncbi.nlm.nih.gov/pubmed/32184732
http://dx.doi.org/10.3389/fphar.2020.00182