MicroRNA exporter HuR clears the internalized pathogens by promoting pro‐inflammatory response in infected macrophages

HuR is a miRNA derepressor protein that can act as miRNA sponge for specific miRNAs to negate their action on target mRNAs. Here we have identified how HuR, by inducing extracellular vesicles‐mediated export of miRNAs, ensures robust derepression of miRNA‐repressed cytokines essential for strong pro...

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Detalles Bibliográficos
Autores principales: Goswami, Avijit, Mukherjee, Kamalika, Mazumder, Anup, Ganguly, Satarupa, Mukherjee, Ishita, Chakrabarti, Saikat, Roy, Syamal, Sundar, Shyam, Chattopadhyay, Krishnananda, Bhattacharyya, Suvendra N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059013/
https://www.ncbi.nlm.nih.gov/pubmed/32031337
http://dx.doi.org/10.15252/emmm.201911011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059013/
https://www.ncbi.nlm.nih.gov/pubmed/32031337
http://dx.doi.org/10.15252/emmm.201911011

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