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Impaired Fluid Intake, but Not Sodium Appetite, in Aged Rats Is Mediated by the Cyclooxygenase-Prostaglandin E(2) Pathway

Aging results in decreased fluid intake following dehydration and other dipsogenic stimuli; similar reductions in sodium intake have also been observed with aging. Given that cyclooxygenase (COX)-derived prostanoids are elevated in aged rats in the midbrain and proinflammatory prostanoids are known...

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Detalles Bibliográficos
Autores principales: Begg, Denovan P., Sinclair, Andrew J., Weisinger, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059018/
https://www.ncbi.nlm.nih.gov/pubmed/32184716
http://dx.doi.org/10.3389/fnagi.2020.00019