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Design, Synthesis, Molecular Modeling Studies and Biological Evaluation of N′-Arylidene-6-(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbohydrazide Derivatives as Novel Anti-HCV Agents

HCV-induced hepatitis is one of the most debilitating diseases. The limited number of anti-HCV drugs and drug-resistance necessitate developing of new scaffolds with different mode of actions. HCV non-structural protein 5B (NS5B) is an attractive target for development of novel inhibitors of HCV rep...

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Detalles Bibliográficos
Autores principales: Mahboubi Rabbani, Sayyed Mohammad Ismaeil, Vahabpour, Rouhollah, Hajimahdi, Zahra, Zarghi, Afshin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059030/
https://www.ncbi.nlm.nih.gov/pubmed/32184846
http://dx.doi.org/10.22037/ijpr.2019.112186.13586