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Design, Synthesis, Molecular Modeling Studies and Biological Evaluation of N′-Arylidene-6-(benzyloxy)-4-oxo-1,4-dihydroquinoline-3-carbohydrazide Derivatives as Novel Anti-HCV Agents
HCV-induced hepatitis is one of the most debilitating diseases. The limited number of anti-HCV drugs and drug-resistance necessitate developing of new scaffolds with different mode of actions. HCV non-structural protein 5B (NS5B) is an attractive target for development of novel inhibitors of HCV rep...
Autores principales: | Mahboubi Rabbani, Sayyed Mohammad Ismaeil, Vahabpour, Rouhollah, Hajimahdi, Zahra, Zarghi, Afshin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Shaheed Beheshti University of Medical Sciences
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059030/ https://www.ncbi.nlm.nih.gov/pubmed/32184846 http://dx.doi.org/10.22037/ijpr.2019.112186.13586 |
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