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Construction of a Mammalian IRES-based Expression Vector to Amplify a Bispecific Antibody; Blinatumomab

Blinatumomab, the bispecific T cell engager antibody (BsAb), has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression...

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Detalles Bibliográficos
Autores principales: Naddafi, Fatemeh, Davami, Fatemeh, Tabarzad, Maryam, Barkhordari, Farzaneh, Shirazi, Farshad H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059065/
https://www.ncbi.nlm.nih.gov/pubmed/32184875
http://dx.doi.org/10.22037/ijpr.2019.14387.12351