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Construction of a Mammalian IRES-based Expression Vector to Amplify a Bispecific Antibody; Blinatumomab
Blinatumomab, the bispecific T cell engager antibody (BsAb), has been demonstrated as the most successful BsAb to date. Throughout the past decade, vector design has great importance for the expression of monoclonal antibody in Chinese hamster ovary (CHO) cells. It has been indicated that expression...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Shaheed Beheshti University of Medical Sciences
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059065/ https://www.ncbi.nlm.nih.gov/pubmed/32184875 http://dx.doi.org/10.22037/ijpr.2019.14387.12351 |