Slowing of the Time Course of Acidification Decreases the Acid-Sensing Ion Channel 1a Current Amplitude and Modulates Action Potential Firing in Neurons

Acid-sensing ion channels (ASICs) are H(+)-activated neuronal Na(+) channels. They are involved in fear behavior, learning, neurodegeneration after ischemic stroke and in pain sensation. ASIC activation has so far been studied only with fast pH changes, although the pH changes associated with many r...

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Detalles Bibliográficos
Autores principales: Alijevic, Omar, Bignucolo, Olivier, Hichri, Echrak, Peng, Zhong, Kucera, Jan P., Kellenberger, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059123/
https://www.ncbi.nlm.nih.gov/pubmed/32180707
http://dx.doi.org/10.3389/fncel.2020.00041

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059123/
https://www.ncbi.nlm.nih.gov/pubmed/32180707
http://dx.doi.org/10.3389/fncel.2020.00041

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