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Formulation and Characterization of Solid Lipid Nanoparticles Loading RF22-c, a Potent and Selective 5-LO Inhibitor, in a Monocrotaline-Induced Model of Pulmonary Hypertension

Pulmonary arterial hypertension (PAH) is a rare but fatal disease characterized by persistent elevated blood pressure in the pulmonary circulation, due to increased resistance to blood flow, through the lungs. Advances in the understanding of the pathobiology of PAH clarify the role of leukotrienes...

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Detalles Bibliográficos
Autores principales: Liparulo, Angela, Esposito, Renata, Santonocito, Debora, Muñoz-Ramírez, Alejandra, Spaziano, Giuseppe, Bruno, Ferdinando, Xiao, Jianbo, Puglia, Carmelo, Filosa, Rosanna, Berrino, Liberato, D'Agostino, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059131/
https://www.ncbi.nlm.nih.gov/pubmed/32180715
http://dx.doi.org/10.3389/fphar.2020.00083