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Formulation and Characterization of Solid Lipid Nanoparticles Loading RF22-c, a Potent and Selective 5-LO Inhibitor, in a Monocrotaline-Induced Model of Pulmonary Hypertension
Pulmonary arterial hypertension (PAH) is a rare but fatal disease characterized by persistent elevated blood pressure in the pulmonary circulation, due to increased resistance to blood flow, through the lungs. Advances in the understanding of the pathobiology of PAH clarify the role of leukotrienes...
Autores principales: | Liparulo, Angela, Esposito, Renata, Santonocito, Debora, Muñoz-Ramírez, Alejandra, Spaziano, Giuseppe, Bruno, Ferdinando, Xiao, Jianbo, Puglia, Carmelo, Filosa, Rosanna, Berrino, Liberato, D'Agostino, Bruno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059131/ https://www.ncbi.nlm.nih.gov/pubmed/32180715 http://dx.doi.org/10.3389/fphar.2020.00083 |
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