Cargando…

Inhibiting MARSs reduces hyperhomocysteinemia‐associated neural tube and congenital heart defects

Hyperhomocysteinemia is a common metabolic disorder that imposes major adverse health consequences. Reducing homocysteine levels, however, is not always effective against hyperhomocysteinemia‐associated pathologies. Herein, we report the potential roles of methionyl‐tRNA synthetase (MARS)‐generated...

Descripción completa

Detalles Bibliográficos
Autores principales: Mei, Xinyu, Qi, Dashi, Zhang, Ting, Zhao, Ying, Jin, Li, Hou, Junli, Wang, Jianhua, Lin, Yan, Xue, Yu, Zhu, Pingping, Liu, Zexian, Huang, Lei, Nie, Ji, Si, Wen, Ma, Jingyi, Ye, Jianhong, Finnell, Richard H, Saiyin, Hexige, Wang, Hongyan, Zhao, Jianyuan, Zhao, Shimin, Xu, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059139/
https://www.ncbi.nlm.nih.gov/pubmed/32003121
http://dx.doi.org/10.15252/emmm.201809469