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miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease

MicroRNAs play a pivotal role in rapid, dynamic, and spatiotemporal modulation of synaptic functions. Among them, recent emerging evidence highlights that microRNA‐181a (miR‐181a) is particularly abundant in hippocampal neurons and controls the expression of key plasticity‐related proteins at synaps...

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Detalles Bibliográficos
Autores principales: Rodriguez‐Ortiz, Carlos J., Prieto, Gilberto Aleph, Martini, Alessandra C., Forner, Stefania, Trujillo‐Estrada, Laura, LaFerla, Frank M., Baglietto‐Vargas, David, Cotman, Carl W., Kitazawa, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059142/
https://www.ncbi.nlm.nih.gov/pubmed/32087004
http://dx.doi.org/10.1111/acel.13118