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miR‐181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer’s disease
MicroRNAs play a pivotal role in rapid, dynamic, and spatiotemporal modulation of synaptic functions. Among them, recent emerging evidence highlights that microRNA‐181a (miR‐181a) is particularly abundant in hippocampal neurons and controls the expression of key plasticity‐related proteins at synaps...
Autores principales: | Rodriguez‐Ortiz, Carlos J., Prieto, Gilberto Aleph, Martini, Alessandra C., Forner, Stefania, Trujillo‐Estrada, Laura, LaFerla, Frank M., Baglietto‐Vargas, David, Cotman, Carl W., Kitazawa, Masashi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059142/ https://www.ncbi.nlm.nih.gov/pubmed/32087004 http://dx.doi.org/10.1111/acel.13118 |
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