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“Amyloid‐beta accumulation cycle” as a prevention and/or therapy target for Alzheimer's disease

The cell cycle and its regulators are validated targets for cancer drugs. Reagents that target cells in a specific cell cycle phase (e.g., antimitotics or DNA synthesis inhibitors/replication stress inducers) have demonstrated success as broad‐spectrum anticancer drugs. Cyclin‐dependent kinases (CDK...

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Detalles Bibliográficos
Autores principales: Rao, Chinthalapally V., Asch, Adam S., Carr, Daniel J. J., Yamada, Hiroshi Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059149/
https://www.ncbi.nlm.nih.gov/pubmed/31981470
http://dx.doi.org/10.1111/acel.13109