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Heparinized chitosan stabilizes the bioactivity of BMP-2 and potentiates the osteogenic efficacy of demineralized bone matrix

BACKGROUND: Demineralized bone matrix (DBM), an allograft bone processed to better expose osteoinductive factors such as bone morphogenetic proteins (BMPs), is increasingly used for clinical bone repair. However, more extensive use of DBM is limited by its unpredictable osteoinductivity and low bone...

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Detalles Bibliográficos
Autores principales: Kim, Soyon, Fan, Jiabing, Lee, Chung-Sung, Chen, Chen, Bubukina, Ksenia, Lee, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059291/
https://www.ncbi.nlm.nih.gov/pubmed/32165922
http://dx.doi.org/10.1186/s13036-020-0231-y