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Myoblasts With Higher IRS-1 Levels Are Eliminated From the Normal Cell Layer During Differentiation

Insulin receptor substrate (IRS)-1 is a major substrate of insulin-like growth factor (IGF)-I receptors. It is well-known that IGF-I and II play essential roles in myogenesis progression. Herein, we report an unexpected phenomenon that IRS-1-overexpressing L6 myoblasts are eliminated from normal cel...

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Detalles Bibliográficos
Autores principales: Okino, Ryosuke, Usui, Ami, Yoneyama, Yosuke, Takahashi, Shin-Ichiro, Hakuno, Fumihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059307/
https://www.ncbi.nlm.nih.gov/pubmed/32180762
http://dx.doi.org/10.3389/fendo.2020.00096