ADMET evaluation in drug discovery. 20. Prediction of breast cancer resistance protein inhibition through machine learning

Breast cancer resistance protein (BCRP/ABCG2), an ATP-binding cassette (ABC) efflux transporter, plays a critical role in multi-drug resistance (MDR) to anti-cancer drugs and drug–drug interactions. The prediction of BCRP inhibition can facilitate evaluating potential drug resistance and drug–drug i...

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Detalles Bibliográficos
Autores principales: Jiang, Dejun, Lei, Tailong, Wang, Zhe, Shen, Chao, Cao, Dongsheng, Hou, Tingjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059329/
https://www.ncbi.nlm.nih.gov/pubmed/33430990
http://dx.doi.org/10.1186/s13321-020-00421-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059329/
https://www.ncbi.nlm.nih.gov/pubmed/33430990
http://dx.doi.org/10.1186/s13321-020-00421-y

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