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Toxic tau: structural origins of tau aggregation in Alzheimer's disease

Alzheimer’s disease is characterized by the extracellular accumulation of the amyloid β in the form of amyloid plaques and the intracellular deposition of the microtubule-associated protein tau in the form of neurofibrillary tangles. Most of the Alzheimer’s drugs targeting amyloid β have been failed...

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Detalles Bibliográficos
Autores principales: Mamun, Abdullah Al, Uddin, Md. Sahab, Mathew, Bijo, Ashraf, Ghulam Md
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059584/
https://www.ncbi.nlm.nih.gov/pubmed/31997800
http://dx.doi.org/10.4103/1673-5374.274329