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Upstream ORFs Influence Translation Efficiency in the Parasite Trypanosoma cruzi

It is generally accepted that the presence of ORFs in the 5′ untranslated region of eukaryotic transcripts modulates the production of proteins by controlling the translation initiation rate of the main CDS. In trypanosomatid parasites, which almost exclusively depend on post-transcriptional mechani...

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Detalles Bibliográficos
Autores principales: Radío, Santiago, Garat, Beatriz, Sotelo-Silveira, José, Smircich, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059621/
https://www.ncbi.nlm.nih.gov/pubmed/32180802
http://dx.doi.org/10.3389/fgene.2020.00166