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The pivotal role of micro-environmental cells in a human blood–brain barrier in vitro model of cerebral ischemia: functional and transcriptomic analysis

BACKGROUND: The blood–brain barrier (BBB) is altered in several diseases of the central nervous system. For example, the breakdown of the BBB during cerebral ischemia in stroke or traumatic brain injury is a hallmark of the diseases’ progression. This functional damage is one key event which is atte...

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Detalles Bibliográficos
Autores principales: Gerhartl, Anna, Pracser, Nadja, Vladetic, Alexandra, Hendrikx, Sabrina, Friedl, Heinz-Peter, Neuhaus, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059670/
https://www.ncbi.nlm.nih.gov/pubmed/32138745
http://dx.doi.org/10.1186/s12987-020-00179-3