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Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer

BACKGROUND: Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer with highly invasive ability and metastatic nature to the lymph nodes. Long non-coding RNAs (lncRNAs) have been widely explored in cancer tumorigenesis and progression. However, their roles in TNBC lymph...

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Detalles Bibliográficos
Autores principales: Zheng, Shaoquan, Yang, Lu, Zou, Yutian, Liang, Jie-ying, Liu, Peng, Gao, Guanfeng, Yang, Anli, Tang, Hailin, Xie, Xiaoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059688/
https://www.ncbi.nlm.nih.gov/pubmed/32138762
http://dx.doi.org/10.1186/s13045-020-00852-y