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SEPT9_v2, frequently silenced by promoter hypermethylation, exerts anti-tumor functions through inactivation of Wnt/β-catenin signaling pathway via miR92b-3p/FZD10 in nasopharyngeal carcinoma cells

BACKGROUND: Nasopharyngeal carcinoma tends to present at an advanced stage because the primary anatomic site is located in a less visible area and its clinical symptoms are nonspecific. Prognosis of advanced nasopharyngeal carcinoma cases remains disappointing. SEPT9 is a methylation-based biomarker...

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Detalles Bibliográficos
Autores principales: Jiang, Yu, Liu, Lei, Xiang, Qin, He, Xiaoqian, Wang, Yan, Zhou, Dishu, Zou, Can, Chen, Qian, Peng, Mingyu, He, Jin, Jiang, Xianyao, Xiang, Tingxiu, Yang, Yucheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059696/
https://www.ncbi.nlm.nih.gov/pubmed/32138771
http://dx.doi.org/10.1186/s13148-020-00833-5