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SODA: prediction of protein solubility from disorder and aggregation propensity

Solubility is an important, albeit not well understood, feature determining protein behavior. It is of paramount importance in protein engineering, where similar folded proteins may behave in very different ways in solution. Here we present SODA, a novel method to predict the changes of protein solu...

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Detalles Bibliográficos
Autores principales: Paladin, Lisanna, Piovesan, Damiano, Tosatto, Silvio C. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059794/
https://www.ncbi.nlm.nih.gov/pubmed/28505312
http://dx.doi.org/10.1093/nar/gkx412