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Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells

Silibinin exhibits antidiabetic potential by preserving the mass and function of pancreatic β-cells through up-regulation of estrogen receptor-α (ERα) expression. However, the underlying protective mechanism of silibinin in pancreatic β-cells is still unclear. In the current study, we sought to dete...

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Detalles Bibliográficos
Autores principales: Chu, Chun, Gao, Xiang, Li, Xiang, Zhang, Xiaoying, Ma, Ruixin, Jia, Ying, Li, Dahong, Wang, Dongkai, Xu, Fanxing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059807/
https://www.ncbi.nlm.nih.gov/pubmed/31649209
http://dx.doi.org/10.4062/biomolther.2019.071