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Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells
Silibinin exhibits antidiabetic potential by preserving the mass and function of pancreatic β-cells through up-regulation of estrogen receptor-α (ERα) expression. However, the underlying protective mechanism of silibinin in pancreatic β-cells is still unclear. In the current study, we sought to dete...
Autores principales: | Chu, Chun, Gao, Xiang, Li, Xiang, Zhang, Xiaoying, Ma, Ruixin, Jia, Ying, Li, Dahong, Wang, Dongkai, Xu, Fanxing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059807/ https://www.ncbi.nlm.nih.gov/pubmed/31649209 http://dx.doi.org/10.4062/biomolther.2019.071 |
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