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Polyphenolic Biflavonoids Inhibit Amyloid-Beta Fibrillation and Disaggregate Preformed Amyloid-Beta Fibrils

Alzheimer’s disease (AD) is a devastating neurodegenerative disease and a major cause of dementia in elderly individuals world-wide. Increased deposition of insoluble amyloid β (Aβ) fibrils in the brain is thought be a key neuropathological hallmark of AD. Many recent studies show that natural produ...

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Detalles Bibliográficos
Autores principales: Choi, Erika Y., Kang, Sam Sik, Lee, Sang Kook, Han, Byung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7059817/
https://www.ncbi.nlm.nih.gov/pubmed/31697876
http://dx.doi.org/10.4062/biomolther.2019.113