Folate-Mediated Targeted Delivery of siPLK1 by Leucine-Bearing Polyethylenimine

BACKGROUND: siRNA-mediated polo-like kinase 1 (PLK1) silencing has been proposed as a promising therapeutic method for multiple cancers. However, the clinic application of this method is still hindered by the low specific delivery of siPLK1 to desired tumor lesions. Herein, folate (FA)-modified and...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Lu, Song, Zheyu, Xu, Zhonghang, Wu, Yuanyu, Shi, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060029/
https://www.ncbi.nlm.nih.gov/pubmed/32184594
http://dx.doi.org/10.2147/IJN.S227289

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060029/
https://www.ncbi.nlm.nih.gov/pubmed/32184594
http://dx.doi.org/10.2147/IJN.S227289

Ejemplares similares