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Folate-Mediated Targeted Delivery of siPLK1 by Leucine-Bearing Polyethylenimine
BACKGROUND: siRNA-mediated polo-like kinase 1 (PLK1) silencing has been proposed as a promising therapeutic method for multiple cancers. However, the clinic application of this method is still hindered by the low specific delivery of siPLK1 to desired tumor lesions. Herein, folate (FA)-modified and...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060029/ https://www.ncbi.nlm.nih.gov/pubmed/32184594 http://dx.doi.org/10.2147/IJN.S227289 |