High-throughput, single-particle tracking reveals nested membrane domains that dictate KRas(G12D) diffusion and trafficking

Membrane nanodomains have been implicated in Ras signaling, but what these domains are and how they interact with Ras remain obscure. Here, using single particle tracking with photoactivated localization microscopy (spt-PALM) and detailed trajectory analysis, we show that distinct membrane domains d...

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Detalles Bibliográficos
Autores principales: Lee, Yerim, Phelps, Carey, Huang, Tao, Mostofian, Barmak, Wu, Lei, Zhang, Ying, Tao, Kai, Chang, Young Hwan, Stork, Philip JS, Gray, Joe W, Zuckerman, Daniel M, Nan, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Physics of Living Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060040/
https://www.ncbi.nlm.nih.gov/pubmed/31674905
http://dx.doi.org/10.7554/eLife.46393

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060040/
https://www.ncbi.nlm.nih.gov/pubmed/31674905
http://dx.doi.org/10.7554/eLife.46393

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