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Spatiotemporal dynamics of multi-vesicular release is determined by heterogeneity of release sites within central synapses

A synaptic active zone (AZ) can release multiple vesicles in response to an action potential. This multi-vesicular release (MVR) occurs at most synapses, but its spatiotemporal properties are unknown. Nanoscale-resolution detection of individual release events in hippocampal synapses revealed unprec...

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Detalles Bibliográficos
Autores principales: Maschi, Dario, Klyachko, Vitaly A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060041/
https://www.ncbi.nlm.nih.gov/pubmed/32026806
http://dx.doi.org/10.7554/eLife.55210