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Spatiotemporal dynamics of multi-vesicular release is determined by heterogeneity of release sites within central synapses
A synaptic active zone (AZ) can release multiple vesicles in response to an action potential. This multi-vesicular release (MVR) occurs at most synapses, but its spatiotemporal properties are unknown. Nanoscale-resolution detection of individual release events in hippocampal synapses revealed unprec...
Autores principales: | Maschi, Dario, Klyachko, Vitaly A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060041/ https://www.ncbi.nlm.nih.gov/pubmed/32026806 http://dx.doi.org/10.7554/eLife.55210 |
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