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Microfluidic platform for three-dimensional cell culture under spatiotemporal heterogeneity of oxygen tension

Cells in a tumor microenvironment are exposed to spatial and temporal variations in oxygen tension due to hyperproliferation and immature vascularization. Such spatiotemporal oxygen heterogeneity affects the behavior of cancer cells, leading to cancer growth and metastasis, and thus, it is essential...

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Detalles Bibliográficos
Autores principales: Koens, Rei, Tabata, Yugo, Serrano, Jean C., Aratake, Satoshi, Yoshino, Daisuke, Kamm, Roger D., Funamoto, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060087/
https://www.ncbi.nlm.nih.gov/pubmed/32161836
http://dx.doi.org/10.1063/1.5127069