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The Mechanism of Cancer Drug Addiction in ALK-Positive T-Cell Lymphoma

Rational new strategies are needed to treat tumors resistant to kinase inhibitors. Mechanistic studies of resistance provide fertile ground for development of new approaches. Cancer drug addiction is a paradoxical resistance phenomenon, well-described in MEK-ERK-driven solid tumors, in which drug-ta...

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Detalles Bibliográficos
Autores principales: Rajan, Soumya S., Amin, Amit Dipak, Li, Lingxiao, Rolland, Delphine C., Li, Haiquan, Kwon, Deukwoo, Kweh, Mercedes F., Arumov, Artavazd, Roberts, Evan R., Yan, Aimin, Basrur, Venkatesha, Elenitoba-Johnson, Kojo S.J, Chen, Xi Steven, Puvvada, Soham D., Lussier, Yves A., Bilbao, Daniel, Lim, Megan S., Schatz, Jonathan H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060126/
https://www.ncbi.nlm.nih.gov/pubmed/31804622
http://dx.doi.org/10.1038/s41388-019-1136-4