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A novel mutation in the mouse Pcsk1 gene showing obesity and diabetes

The proprotein convertase subtilisin/Kexin type 1 (PCSK1/PC1) protein processes inactive pro-hormone precursors into biologically active hormones in a number of neuroendocrine and endocrine cell types. Patients with recessive mutations in PCSK1 exhibit a complex spectrum of traits including obesity,...

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Detalles Bibliográficos
Autores principales: Muhsin, Nor I. A., Bentley, Liz, Bai, Ying, Goldsworthy, Michelle, Cox, Roger D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060156/
https://www.ncbi.nlm.nih.gov/pubmed/31974728
http://dx.doi.org/10.1007/s00335-020-09826-4