Rapid Pyrazinamide Drug Susceptibility Testing using a Closed-Tube PCR Assay of the Entire pncA gene

The continued use of pyrazinamide in the treatment of tuberculosis in the absence of a rapid, accurate and standardized pyrazinamide drug susceptibility assays is of great concern. While whole genome sequencing holds promise, it is not yet feasible option in low resource settings as it requires expe...

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Detalles Bibliográficos
Autores principales: Whitfield, Michael G., Marras, Salvatore A. E., Warren, Rob M., Van Rie, Annelies, Rice, John, Wangh, Lawrence J., Kreiswirth, Barry N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060184/
https://www.ncbi.nlm.nih.gov/pubmed/32144379
http://dx.doi.org/10.1038/s41598-020-61286-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060184/
https://www.ncbi.nlm.nih.gov/pubmed/32144379
http://dx.doi.org/10.1038/s41598-020-61286-7

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