Liquid-liquid phase separation and extracellular multivalent interactions in the tale of galectin-3

Liquid-liquid phase separation (LLPS) explains many intracellular activities, but its role in extracellular functions has not been studied to the same extent. Here we report how LLPS mediates the extracellular function of galectin-3, the only monomeric member of the galectin family. The mechanism th...

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Detalles Bibliográficos
Autores principales: Chiu, Yi-Ping, Sun, Yung-Chen, Qiu, De-Chen, Lin, Yu-Hao, Chen, Yin-Quan, Kuo, Jean-Cheng, Huang, Jie-rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060198/
https://www.ncbi.nlm.nih.gov/pubmed/32144274
http://dx.doi.org/10.1038/s41467-020-15007-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060198/
https://www.ncbi.nlm.nih.gov/pubmed/32144274
http://dx.doi.org/10.1038/s41467-020-15007-3

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