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Liquid-liquid phase separation and extracellular multivalent interactions in the tale of galectin-3
Liquid-liquid phase separation (LLPS) explains many intracellular activities, but its role in extracellular functions has not been studied to the same extent. Here we report how LLPS mediates the extracellular function of galectin-3, the only monomeric member of the galectin family. The mechanism th...
Autores principales: | Chiu, Yi-Ping, Sun, Yung-Chen, Qiu, De-Chen, Lin, Yu-Hao, Chen, Yin-Quan, Kuo, Jean-Cheng, Huang, Jie-rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060198/ https://www.ncbi.nlm.nih.gov/pubmed/32144274 http://dx.doi.org/10.1038/s41467-020-15007-3 |
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