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Long non-coding RNA HOTAIR knockdown enhances radiosensitivity through regulating microRNA-93/ATG12 axis in colorectal cancer

Colorectal cancer (CRC) is a global healthcare problem. Radioresistance is a huge setback for CRC radiotherapy. In this text, the roles and molecular mechanisms of long non-coding RNA HOTAIR in CRC tumorigenesis and radioresistance were further investigated. ATG12 mRNA, HOTAIR, and microRNA-93 (miR-...

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Detalles Bibliográficos
Autores principales: Liu, Yingqiang, Chen, Xijuan, Chen, Xiling, Liu, Junqi, Gu, Hao, Fan, Ruitai, Ge, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060216/
https://www.ncbi.nlm.nih.gov/pubmed/32144238
http://dx.doi.org/10.1038/s41419-020-2268-8