A high-throughput screening platform for Polycystic Kidney Disease (PKD) drug repurposing utilizing murine and human ADPKD cells

Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common inherited monogenic disorders, characterized by a progressive decline in kidney function due in part to the formation of fluid-filled cysts. While there is one FDA-approved therapy, it is associated with potential adverse...

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Detalles Bibliográficos
Autores principales: Asawa, Rosita R., Danchik, Carina, Zakharov, Alexey, Chen, Yuchi, Voss, Ty, Jadhav, Ajit, Wallace, Darren P., Trott, Josephine F., Weiss, Robert H., Simeonov, Anton, Martinez, Natalia J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060218/
https://www.ncbi.nlm.nih.gov/pubmed/32144367
http://dx.doi.org/10.1038/s41598-020-61082-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060218/
https://www.ncbi.nlm.nih.gov/pubmed/32144367
http://dx.doi.org/10.1038/s41598-020-61082-3

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