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Context-dependent selection as the keystone in the somatic evolution of cancer
Somatic evolution of cancer involves a series of mutations, and attendant changes, in one or more clones of cells. A “bad luck” type model assumes chance accumulation of mutations. The clonal expansion model assumes, on the other hand, that any mutation leading to partial loss of regulation of cell...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7060219/ https://www.ncbi.nlm.nih.gov/pubmed/32144283 http://dx.doi.org/10.1038/s41598-020-61046-7 |